Search results for Hypoxia-inducible factor 1-alpha

Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody, Abbexa, abx125940

HIF1a Antibody is a Rabbit Polyclonal against HIF1a.

Hypoxia inducible factor-1 alpha antibody (H1alpha67), Covalab, Ref 00028903

Hypoxia inducible factor-1 alpha antibody (HA111), Covalab, Ref 00035807

Hypoxia Inducible Factor 1 Alpha (HIF1A) Antibody, Abbexa, abx239939

Hypoxia Inducible Factor 1 Alpha (HIF1A) Antibody is a Mouse Monoclonal antibody for the detection of HIF1a. Under normal oxygen conditions, HIF1a is continuously produced and destroyed, in a process involving hydroxylation, interaction with von Hippel-Lindau (VHL) protein, polyubiquitylation and subsequent proteasomal degradation. Under hypoxic conditions, hydroxylation is impaired and HIF1a is stabilized. HIF1a localizes in cytoplasm in normoxia, but it can translocate into nuclear in response to hypoxia. The calculated molecular weight of HIF1a is 93 kDa, but the modified protein HIF1a is about 110-120kDa (PMID: 11698256,.PMID: 7539918).

Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody, Abbexa, abx403048

Human Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody is a Mouse monoclonal against Hypoxia Inducible Factor 1 Alpha (HIF1a).

Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody, Abbexa, abx172856

This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody is a Mouse Monoclonal antibody against Hypoxia Inducible Factor 1 Alpha (HIF1a).

Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody, Abbexa, abx103439

Polyclonal Antibody to HIF1a (HIF1a).

Hypoxia Inducible Factor 1 Alpha (HIF1A) Antibody, Abbexa, abx240089

Hypoxia Inducible Factor 1 Alpha (HIF1A) Antibody is a Rabbit Polyclonal antibody for the detection of HIF1a. Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Activation requires recruitment of transcriptional coactivators such as CREBPB and EP300. Activity is enhanced by interaction with both, NCOA1 or NCOA2. Interaction with redox regulatory protein APEX seems to activate CTAD and potentiates activation by NCOA1 and CREBBP. Involved in the axonal distribution and transport of mitochondria in neurons during hypoxia.

Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody, Abbexa, abx110424

Hypoxia-inducible factor 1-alpha Antibody is a Rabbit Polyclonal antibody against Hypoxia-inducible factor 1-alpha.

Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody, Abbexa, abx132409

Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody is a Mouse Monoclonal against Hypoxia Inducible Factor 1 Alpha (HIF1a).