Search results for db

IRS2 (pY978) Antibody, Abbexa, abx032045

Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

Microtubule-Associated Protein Tau (MAPT) Antibody (APC), Abbexa, abx450164

Microtubule-Associated Protein Tau (MAPT) Antibody (APC) is a Mouse Monoclonal against Microtubule-Associated Protein Tau (MAPT).

RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474) Antibody, Abbexa, abx031949

AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.

Amyloid Fibrils (OC) Antibody (ATTO594), Abbexa, abx448317

Amyloid Fibrils (OC) Antibody (ATTO594) is a Rabbit Polyclonal against Amyloid.

JMJD2B (pS566) Antibody, Abbexa, abx032109

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

TSC1 (pT390) Antibody, Abbexa, abx032282

This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.

MAP3K7 (pT187) Antibody, Abbexa, abx031943

MAP3K7 is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.

Anti-DENV-1/3/4 Envelope protein E/EDIII domain Antibody (2H12), AntibodySystem, RVV19934

BAD (pS96) Antibody, Abbexa, abx032255

BAD promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

S15 Oligopeptide (S Tag) Antibody, Abbexa, abx132416

This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. S15 Oligopeptide (S) Tag Antibody is a Mouse Monoclonal against S15 Oligopeptide (S) Tag.