Isotype Controls

Human IgG3 Isotype Control Antibody, InvivoGen, bgal-mab3

Human IgG4 Isotype Control Antibody, InvivoGen, bgal-mab4

Human IgG4 (S228P) Isotype Control Antibody, InvivoGen, bgal-mab114

β-Gal / β-Galactosidase antibody for ADC (isotype control), InvivoGen, bgal-mab1-1

InvivoGen provides Anti-β-Gal-hIgG1*, a monoclonal antibody (mAb) specifically developed for the generation of controlantibody-drug conjugates (ADCs). This mAb features: InvivoGen's Anti-β-Gal-hIgG1* has been generated by recombinant DNA technology, produced in CHO cells, and purified by affinity chromatography.

Human CD19 x E. coli β-Gal Bispecific Antibody - Negative control, InvivoGen, bimab-cd19bg-01

Human EpCAM x E. coli β-Gal Bispecific Antibody - Negative Control, InvivoGen, bimab-ecambg-01

Anti-hEpCAM-βGalis a bispecific antibody that recognizes two sites: human epithelial cell adhesion molecule (hEpCAM) andE. coliβ-galactosidase (β-Gal). It is used as a negative control for the Anti-hEpCAM-CD3 bispecific antibody that, like solitomab, engages unstimulated T cells to proliferate and exert cytotoxic activity on EpCAM-positive tumor cells [1]. Human EpCAM (also known as CD326, Trop1) is a transmembrane, 40 kDa glycoprotein highly abundant in almost all human carcinomas, including colon, prostate, ovarian, or breast cancer [2]. In healthy tissue, EpCAM expression is generally low [1,2]. In cancer, EpCAM overexpression is responsible for tumor proliferation, invasion, and migration. Since it is often correlated with a poor prognosis, EpCAM represents an attractive therapeutic target [1].

Human IgA2 Isotype Control Antibody, InvivoGen, bgal-mab7

Mouse IgG1 Isotype Control Antibody, InvivoGen, mabg1-ctrlm

Mouse IgG2a Isotype Control Antibody, InvivoGen, mabg2a-ctrlm

Mouse IgG2b Isotype Control Antibody, InvivoGen, mabg2b-ctrlm