Search results for IBA1
![Anti-Iba1 antibody [EPR16588] - Microglia marker – Chicken IgY (Chimeric) Brand Logo](https://file.buyantibody.com/public/brand/20260608/Abcam.jpg "Click to View Anti-Iba1 antibody [EPR16588] - Microglia marker – Chicken IgY (Chimeric) Product Detail")
Anti-Iba1 antibody [EPR16588] - Microglia marker – Chicken IgY (Chimeric), Abcam, AB318302
This chicken monoclonal chimeric antibody has been engineered from a RabMAb parent antibody ( ab178846 ). By necessity, some rabbit sequence is retained as part of the variable domain. When multiplexing with other rabbit-derived antibodies, using cross absorbed Fc-reactive secondary antibodies are recommended. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Chicken
Reactivity
Human, Mouse, Rat
Applications
ICC/IF, IHC-Fr, IHC-P
Conjugation
Anti-Iba1 antibody [EPR16588] - Microglia marker - Goat IgG (Chimeric), Abcam, AB289874
What is this antibody validated in? Anti-Iba1 antibody [EPR16588] - Goat IgG (Chimeric) (ab289874) is a goat recombinant monoclonal antibody and is validated for use in Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in House Mouse, Human, Norway Rat samples. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR16588] also available for your convenience: ab178846 , Carrier free - ab220815 , Alexa Fluor ® 488 - ab225260 , Alexa Fluor ® 647 - ab225261 , ab300156 , Carrier free - ab300157 , ab318302 , Carrier free - ab318305 , Alexa Fluor ® 750 - ab321218 What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Goat
Reactivity
Human, Mouse, Rat
Applications
IHC-P, Flow Cyt (Intra), ICC/IF
Conjugation
Anti-Iba1 antibody [EPR16588] - Microglia marker - Rat IgG2a (Chimeric), Abcam, AB300156
Find all reagents to label astrocytes in our " Microglia markers guide ". This rat monoclonal chimeric antibody has been engineered from RabMab parent antibody ( ab178846 ). By necessity, some rabbit sequence is retained as part of the variable domain. When multiplexing with other rabbit-derived antibodies, using across absorbed Fc-reactive secondary antibodies are recommended. ab300156 does not react in: WB with human, mouse, and rat samples; ICC-IF with human tissues. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]
Host
Rat
Reactivity
Human, Mouse, Rat
Applications
IHC-P, Flow Cyt (Intra)
Conjugation
Anti-Iba1 antibody [EPR16589] - Microglia marker - Mouse IgG1 (Chimeric), Abcam, AB283319
Find all reagents to label astrocytes in our " Microglia markers guide ". Anti-Iba1 antibody [EPR16589] - Mouse IgG1 (Chimeric) (ab283319) is a mouse monoclonal recombinant antibody validated for use in IHC-P, IP, WB, ICC/IF and Flow Cyt (Intra) in mouse, rat and human samples. Clone EPR16589 was initially developed by Abcam using patented rabbit monoclonal antibody technology and has been engineered to generate this mouse chimeric antibody which retains the binding properties of the RabMAb parent, but has a mouse Fc region. By necessity, some rabbit sequence is retained as part of the variable domain. When multiplexing with other rabbit-derived antibodies, using cross absorbed Fc-reactive secondary antibodies are recommended. Abcams high quality manufacturing and validation processes ensure Anti-Iba1 antibody [EPR16589] - Mouse IgG1 (Chimeric) (ab283319) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Iba1 antibody [EPR16589] - Mouse IgG1 (Chimeric) (ab283319) specifically detects Iba1 (AIF-1) (UniProt ID: P55008; Molecular weight: 17kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format is also available for Anti-Iba1 antibody [EPR16589] - Mouse IgG1 (Chimeric) - ab312913 . Iba1 (Ionized calcium-binding adapter molecule 1; allograft inflammatory factor 1, AIF1) is a prominent microglial marker extensively used in neuroscience research. Its expression increases in various neurodegenerative conditions, including Alzheimer's disease (AD), indicating microglial activation and neuroinflammation. Researchers utilize Iba1 in stainings to assess microglial response and activity in different models, making it essential for understanding inflammatory processes in the brain. Changes in Iba1 expression provide valuable insights into neuroinflammation, highlighting its importance in studying diseases like AD. This mouse monoclonal chimeric antibody has been engineered from a RabMAb parent antibody ( ab178847 ). By necessity, some rabbit sequence is retained as part of the variable domain. When multiplexing with other rabbit-derived antibodies, using cross absorbed Fc-reactive secondary antibodies are recommended. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Mouse
Reactivity
Rat, Human, Mouse
Applications
IP, IHC-P, Flow Cyt (Intra), WB, ICC/IF
Conjugation
Anti-Iba1 antibody [EPR16589] - Microglia marker - Rat IgG2a (Chimeric), Abcam, AB283346
Find all reagents to label astrocytes in our " Microglia markers guide ". Product Specifications Anti-Iba1 antibody [EPR16589] - Rat IgG2a (Chimeric) (ab283346) is a rat monoclonal recombinant antibody validated for use in IHC-P, IP, WB, ICC/IF and Flow Cyt (Intra) in mouse, rat and human samples. Clone EPR16589 was initially developed by Abcam using patented rabbit monoclonal antibody technology and has been engineered to generate this rat chimeric antibody which retains the binding properties of the RabMAb parent, but has a rat Fc region. By necessity, some rabbit sequence is retained as part of the variable domain. When multiplexing with other rabbit-derived antibodies, using cross absorbed Fc-reactive secondary antibodies are recommended. Anti-Iba1 antibody [EPR16589] - Rat IgG2a (Chimeric) (ab283346) specifically detects Iba1 (AIF-1) (UniProt ID: P55008; Molecular weight: 17kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Quality and Validation Abcams high quality manufacturing and validation processes ensure Anti-Iba1 antibody [EPR16589] - Rat IgG2a (Chimeric) (ab283346) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Target Information Iba1 (Ionized calcium-binding adapter molecule 1; allograft inflammatory factor 1, AIF1) is a prominent microglial marker extensively used in neuroscience research. Its expression increases in various neurodegenerative conditions, including Alzheimer's disease (AD), indicating microglial activation and neuroinflammation. Researchers utilize Iba1 in stainings to assess microglial response and activity in different models, making it essential for understanding inflammatory processes in the brain. Changes in Iba1 expression provide valuable insights into neuroinflammation, highlighting its importance in studying diseases like AD. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rat
Reactivity
Human, Mouse, Rat
Applications
IHC-P, WB, Flow Cyt (Intra), IP, ICC/IF
Conjugation
Alexa Fluor® 750 Anti-Iba1 antibody [EPR16588] - Microglia marker, Abcam, AB321218
Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . How are conjugated primary antibodies validated? This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling. For suitable applications and species reactivity, please refer to the unconjugated version of this clone. Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company. The Alexa Fluor® dye included in this product is provided under an intellectual property license from Life Technologies Corporation. As this product contains the Alexa Fluor® dye, the purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). As this product contains the Alexa Fluor® dye the sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: in manufacturing; (ii) to provide a service, information, or data in return for payment (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are sold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or [email protected].
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ICC/IF, Antibody Labelling, IHC-P, Flow Cyt (Intra), Target Binding Affinity
Conjugation
Alexa Fluor® 750
Alexa Fluor® 750 Anti-Iba1 antibody [EPR16589] - Microglia marker, Abcam, AB321219
Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . How are conjugated primary antibodies validated? This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling. For suitable applications and species reactivity, please refer to the unconjugated version of this clone. Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company. The Alexa Fluor® dye included in this product is provided under an intellectual property license from Life Technologies Corporation. As this product contains the Alexa Fluor® dye, the purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). As this product contains the Alexa Fluor® dye the sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: in manufacturing; (ii) to provide a service, information, or data in return for payment (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are sold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or [email protected].
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ICC/IF, IHC-P, Flow Cyt (Intra), Antibody Labelling, Target Binding Affinity
Conjugation
Alexa Fluor® 750
Alexa Fluor® 488 Anti-Iba1 antibody [EPR16588] - Microglia marker, Abcam, AB225260
What is this antibody validated in? Alexa Fluor® 488 Anti-Iba1 antibody [EPR16588] (ab225260) is a rabbit recombinant monoclonal antibody and is validated for use in Immunohistochemistry (IHC-P) in Human samples. Related products Antibody clone EPR16588 is also available pre-conjugated to a variety of labels for your convenience – Anti-Iba1 Alexa Fluor® 488 [EPR16588] (ab225260). Other related products We have a range of other formats of antibody clone [EPR16588] also available for your convenience: ab178846 , Carrier free - ab220815 , Alexa Fluor® 488 - ab225260, Alexa Fluor® 647 - ab225261 , ab300156 , Carrier free - ab300157 , ab318302 , Carrier free - ab318305 , Alexa Fluor® 750 - ab321218 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company. The Alexa Fluor® dye included in this product is provided under an intellectual property license from Life Technologies Corporation. As this product contains the Alexa Fluor® dye, the purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). As this product contains the Alexa Fluor® dye the sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: in manufacturing; (ii) to provide a service, information, or data in return for payment (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are sold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or [email protected].
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ICC/IF, IHC-P, Flow Cyt (Intra)
Conjugation
Alexa Fluor® 488
Alexa Fluor® 488 Anti-Iba1 antibody [EPR16589] - Microglia marker, Abcam, AB310987
What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . How are conjugated primary antibodies validated? This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling. For suitable applications and species reactivity, please refer to the unconjugated version of this clone.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC-P, Antibody Labelling, Target Binding Affinity, Flow Cyt (Intra), ICC/IF
Conjugation
Alexa Fluor® 488
Alexa Fluor® 555 Anti-Iba1 antibody [EPR16589] - Microglia marker, Abcam, AB313215
What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . How are conjugated primary antibodies validated? This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling. For suitable applications and species reactivity, please refer to the unconjugated version of this clone.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Flow Cyt (Intra), ICC/IF, Target Binding Affinity, Antibody Labelling, IHC-P
Conjugation
Alexa Fluor® 555
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